================================================================================


                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT
     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

       Date of Report (Date of earliest event reported): November 2, 2006



                               NEKTAR THERAPEUTICS
             (Exact name of Registrant as specified in its charter)



         Delaware                       0-24006                   94-3134940
(State or other jurisdiction          (Commission               (IRS Employer
      of incorporation)               File Number)           Identification No.)



                               150 Industrial Road
                          San Carlos, California 94070
              (Address of principal executive offices and Zip Code)


       Registrant's telephone number, including area code: (650) 631-3100



Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:

[ ] Written communications pursuant to Rule 425 under the Securities Act (17
    CFR 230.425)

[ ] Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17
    CFR 240.14a-12)

[ ] Pre-commencement communications pursuant to Rule 14d-2(b) under the
    Exchange Act (17 CFR 240.14d-2(b))

[ ] Pre-commencement communications pursuant to Rule 13e-4(c) under the
    Exchange Act (17 CFR 240.13e-4(c))

================================================================================




Item 2.02 Results of Operations and Financial Condition.

On November 2, 2006,  Nektar  Therapeutics  issued a press  release  (the "Press
Release")  announcing  results for the three month and nine month  periods ended
September  30, 2006. A copy of the Press  Release is attached as Exhibit 99.1 to
this Current Report and is incorporated herein by reference.

The  information  in this report,  including  the exhibit  hereto,  shall not be
deemed  "filed" for  purposes of Section 18 of the  Securities  Exchange  Act of
1934, as amended,  or otherwise  subject to the  liabilities  of that Section or
Sections  11 and  12(a)(2)  of the  Securities  Act of  1933,  as  amended.  The
information  contained  herein  and in the  accompanying  exhibit  shall  not be
incorporated  by  reference  into any filing with the  Securities  and  Exchange
Commission  made by Nektar  Therapeutics,  whether made before or after the date
hereof, regardless of any general incorporation language in such filing.




                                   SIGNATURES

Pursuant to the requirement of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.


                                            By:          /s/ ROBERT CHESS
                                                --------------------------------
                                                           Robert Chess
                                                --------------------------------
                                                Chairman of the Board and Acting
                                                  President and Chief Executive
                                                             Officer

                                            Date: November 2, 2006

                                            By:          /s/ LOUIS DRAPEAU
                                                --------------------------------
                                                           Louis Drapeau
                                                --------------------------------
                                                 Senior Vice President, Finance
                                                   and Chief Financial Officer

                                            Date: November 2, 2006




                                  EXHIBIT INDEX

Exhibit No.  Description
- -----------  -----------

99.1         Earnings Press Release of Nektar Therapeutics dated November 2,
             2006.
                                                                    Exhibit 99.1

        Nektar Announces Third Quarter 2006 Financial Results


    --  Nektar increases revenue estimates and reduces net loss
        estimates for full-year 2006; provides preliminary 2007
        financial guidance;

    --  Exubera(R) (insulin human (rDNA origin)) Inhalation Powder
        available in U.S., Germany, U.K. and Ireland;

    --  Exubera receives multiple awards for innovation;

    --  Nektar pulmonary product (ABIP) for preventing fungal
        infections in immunosuppressed patients receives EU orphan
        drug designation along with FDA Orphan Drug and Fast Track
        designation.


    SAN CARLOS, Calif.--(BUSINESS WIRE)--Nov. 2, 2006--Nektar
Therapeutics (Nasdaq:NKTR) announced today its financial results for
the three months ended September 30, 2006.

    The company reported total revenue of $58.6 million for the three
months ended September 30, 2006 compared to $36.4 million for the
three months ended September 30, 2005. For the three months ended
September 30, 2006, product sales and royalty revenue was $41.5
million compared to $8.5 million in the three months ended September
30, 2005; and contract revenue totaled $15.1 million compared to $23.7
million in the three months ended September 30, 2005. Exubera product
and royalty revenue for the three months ended September 30, 2006 was
$26.9 million.

    Nektar reported a GAAP net loss of $19.6 million or $(0.22) per
share for the three months ended September 30, 2006 compared to a GAAP
net loss of $23.8 million or $(0.28) per share for the three months
ended September 30, 2005.

    Nektar also reported a non-GAAP net loss of $14.0 million or
$(0.16) per share for the three months ended September 30, 2006
compared to a non-GAAP net loss for the three months ended September
30, 2005 of $23.8 million or $(0.28) per share. The non-GAAP net loss
for the three months ended September 30, 2006 excludes $2.9 million of
SFAS 123R non-severance stock based compensation charges and $2.7
million of severance and restructuring charges.

    For the nine months ended September 30, 2006, Nektar reported
total revenue of $147.8 million compared to total revenue of $93.4
million for the nine months ended September 30, 2005. For the nine
months ended September 30, 2006, product and royalty revenue was $98.0
million compared to $20.3 million for the nine months ended September
30, 2005; and contract research revenue totaled $44.3 million compared
to $62.7 million for the nine months ended September 30, 2005. Exubera
product and royalty revenue for the nine months ended September 30,
2006 was $62.5 million.

    For the nine months ended September 30, 2006, Nektar reported a
GAAP net loss of $115.9 or $(1.29) per share compared to a GAAP net
loss for the nine months ended September 30, 2005 of $76.9 million or
$(0.90) per share.

    Nektar also reported a non-GAAP net loss for the nine months ended
September 30, 2006 of $63.3 million or $(0.71) per share compared to a
non-GAAP net loss for the nine months ended September 30, 2005 of
$76.9 million or $(0.90) per share.

    The non-GAAP net loss for the nine months ended September 30, 2006
excludes $13.3 million of SFAS 123R non-severance stock based
compensation charges, $16.4 million of severance charges, $5.2 million
of restructuring charges related to the closing of Nektar U.K.
(Bradford), and a $17.7 million charge for a litigation settlement
with the University of Alabama Huntsville (UAH). See the supplemental
table attached to this press release entitled "Reconciliation of GAAP
Financial Measures to Non-GAAP Financial Measures."

    As of September 30, 2006, Nektar reported cash, cash equivalents,
short-term investments, and investments in marketable securities
totaling approximately $490.9 million compared to $566.4 million as of
December 31, 2005 and $491.1 as of June 30, 2006.

    "With the launch underway, orders from Pfizer have increased.
This, combined with our ability to consistently manufacture Exubera
Inhalers and powder at large scale, have enabled us to increase our
revenue estimates for 2006," said Robert Chess, chairman and acting
CEO. "We are pleased that Exubera is now available in the U.S., and
that Pfizer has begun the process of educating leading diabetes care
physicians and health care professionals.

    "In addition to Exubera, other aspects of our business are moving
forward. Based on the results of our recent clinical end-of-Phase-2
meeting with the Food and Drug Administration (FDA), we anticipate
moving our inhaled Amphotericin B Inhalation Powder (ABIP) into
pivotal testing in 2007, and we are continuing to advance our other
proprietary products. Further, we are making progress on focusing our
business to achieve profitability and long-term sustainable growth and
meeting or exceeding our financial objectives we have set for the
company in 2006."

    Financial Outlook for 2006 and 2007

    Today the company is revising its full year 2006 financial
performance estimates and providing preliminary 2007 financial
performance estimates.

    2006 Estimates

    --  For the full year 2006, Nektar is increasing its total revenue
        estimate range to $190 to $210 million from $170 to $200
        million, including an increase in estimated Exubera
        manufacturing and royalty revenue to $90 to $100 million from
        $70 to $90 million, with most of the Exubera related revenue
        being generated by manufacturing sales of Exubera to Pfizer.

    --  The company is reducing its GAAP net loss estimates to a range
        of $155 to $170 million from $160 to $175 million, and
        non-GAAP net loss to $95 to $110 million from $100 to $115
        million due to increased margins and R&D expenses which are
        lower than planned. Non-GAAP net loss excludes the $17.7
        million UAH litigation settlement charge, $22 million of
        estimated SFAS 123R non-severance stock based compensation
        charges, and approximately $20 million of estimated charges
        related to restructuring and severance. See the supplemental
        table attached to this press release entitled "Reconciliation
        of Non-GAAP Projected Financial Guidance for 2006."

    --  The company is not changing its estimates of 2006 cash, cash
        equivalents, and short-term investments and investments in
        marketable securities which remain at an approximate range of
        $415 to $440 at the end of the year.

    2007 Preliminary Estimates

    The company is providing preliminary financial performance
guidance for the full year 2007 as follows:

    --  Total revenue for 2007 in the range of $210 to $250 million,
        including Exubera revenue of $110 to $130 million, with most
        of the estimated Exubera revenue based on estimated
        manufacturing sales of Exubera to Pfizer.

    --  GAAP net loss of $110 to $130 million.

    --  Non-GAAP net loss of $75 to $95 million. Non-GAAP net loss
        excludes approximately $35 million of estimated SFAS 123R
        stock based compensation charges. See the supplemental table
        attached to this press release entitled "Reconciliation of
        Non-GAAP Projected Financial Guidance for 2007."

    Recent Highlights

    Exubera

    "As the creator of the core technologies for Exubera, we at Nektar
appreciate the recognition of Exubera for its innovation to bring a
better therapy option to diabetes patients," said Dr. John Patton,
co-founder and chief scientific officer, Nektar.

    In September 2006, Exubera received two prestigious awards for
innovation. The Wall Street Journal recognized Exubera first in the
biotechnology and medical category as a technological breakthrough. In
Germany, diabetologists declared Exubera to be the most innovative
diabetes medicine of 2006 as published in trade magazine
"PharmaBarometer."

    In early October 2006, Exubera was also awarded the "Best New
Approved Product (Therapeutic)" at the 19th anniversary of The Biotech
Meeting of CEOs at Laguna Niguel, California, a conference sponsored
by Burrill & Co. and Kleiner Perkins Caufield & Byers. The CEOs voted
on what awards to present to their peers for corporate and individual
achievements.

    During the third quarter, Pfizer presented new Exubera data of
particular importance for the healthcare professionals who treat
diabetes. At the 42nd European Association for the Study of Diabetes
in Copenhagen Denmark, held on September 14, 2006, Pfizer announced
data that adult patients with diabetes who took Exubera were able to
safely maintain good blood sugar control even if they developed a
respiratory infection or were exposed to passive (second-hand)
cigarette smoke. In addition, Pfizer announced that an analysis of a
previously reported study showed that Exubera has the potential to
encourage twice as many people with uncontrolled type 2 diabetes to
try insulin in countries where insulin is commonly delivered with a
pen (44 percent choosing insulin with Exubera availability versus 17
percent choosing insulin without Exubera availability). Finally,
Pfizer also announced that an analysis of five clinical trials showed
that people with either type 1 or type 2 diabetes who used Exubera
gained less weight than those using injectable insulin.

    Exubera is marketed by Pfizer and is a product of a developmental
collaboration between Pfizer and Nektar. Exubera is currently
available in the U.S., U.K., Ireland, and Germany. It has been
approved in the European Union, U.S., Brazil and Mexico.

    Under the agreement between the two companies, Nektar receives
royalties on Exubera sales as well as revenue for the manufacture of
the insulin powder and the Exubera Inhalers.

    Nektar Proprietary Products: Key to Sustainable Growth and
Shareholder Value

    "Our proprietary pipeline is the key to sustainable growth and
shareholder value," said Chess. "Our pulmonary and PEGylation
technologies are proven product engines to develop successful partner
products, and we intend to use them to continue to develop outstanding
products."

    On September 18, 2006, Nektar announced that its Amphotericin B
Inhalation Powder (ABIP) product was granted orphan medicinal product
designation by the European Commission for the prevention of pulmonary
fungal infections in patients deemed at risk. In the U.S., the Food
and Drug Administration (FDA) granted both Fast Track designation and
Orphan Drug designation to ABIP for prevention of pulmonary fungal
infections in patients at risk for aspergillosis due to
immunosuppressive therapy. ABIP recently completed a multi-dose, dose
escalation clinical study in preparation for pivotal trials.

    In October, Nektar had an encouraging clinical end-of-Phase-2
meeting with the FDA regarding its Amphotericin B Inhalation Powder
(ABIP) program. The FDA concurred with Nektar's plan to advance to
pivotal trials in 2007 and did not request additional clinical or
preclinical studies before proceeding.

    Partner Products

    Nektar and its partner, Zelos Therapeutics, a private
biopharmaceutical company focused on developing novel therapies for
patients suffering from osteoporosis, announced on September 21, 2006
the initiation of a Phase 1 clinical trial of an inhaled powder
formulation of Zelos' proprietary parathyroid hormone Ostabolin-C(TM)
(cyclic PTH (1-31)). Nektar and Zelos entered into a collaboration to
develop an inhaleable powder form of Ostabolin-C in January 2005.

    Important Safety Information about Exubera

    Patients should not take Exubera if they have poorly controlled or
unstable lung disease, or if they smoke or have stopped smoking less
than six months prior to starting Exubera treatment. If a patient
starts smoking or resumes smoking, he or she must stop using Exubera
and see a healthcare provider about a different treatment.

    In clinical trials, mean treatment group differences between
Exubera and comparators showed that Exubera was associated with small,
non-progressive declines in lung function relative to comparator
treatments.

    Before starting treatment with Exubera, a healthcare professional
will carry out a simple test to check lung function. This will help to
find out if Exubera is the right treatment for individual patients.
Once a patient starts treatment, it is recommended that a healthcare
provider check lung function again at six months and yearly
thereafter.

    Like all medicines, Exubera can cause side effects. As with all
forms of insulin, a possible side effect of Exubera is low blood sugar
levels.

    Some patients have reported a mild cough while taking Exubera,
which tended to occur within seconds to minutes after Exubera
inhalation. Coughing occurred less frequently as patients continued to
use Exubera.

    Conference Call Information

    Robert Chess, Nektar chairman and acting CEO, will host a
conference call for analysts and investors today beginning at 2:00
p.m. Pacific time to discuss further the company's performance.

    Investors can access a live audio-only webcast through a link that
is posted on the Investor Relations section of Nektar's website at
http://www.nektar.com. The web broadcast of the conference call will
be available for replay through November 16, 2006.

    Analysts and investors can also access the conference call live
via telephone by dialing (800) 640-9765 (U.S.); (847) 413-4837
(international). The passcode is 16034200 and the host is Robert
Chess. An audio replay will be available shortly following the call
through November 16, 2006 and can be accessed by dialing (877)
213-9653 (U.S.); or (630) 652-3041 (international) with a passcode of
16034200. In the event that any non-GAAP financial measure is
discussed on the conference call that is not described in the press
release, related information will be made available on the Investor
Relations page at the Nektar website as soon as practical after the
conclusion of the conference call.

    About Nektar

    Nektar Therapeutics is a biopharmaceutical company that develops
and enables differentiated therapeutics with its industry-leading
pulmonary and PEGylation technologies, expertise and manufacturing
capabilities. Nektar technology and know-how have enabled nine
approved products for partners, which include the world's leading
pharmaceutical and biotechnology companies. Nektar also develops its
own products by applying its technologies and expertise to existing
medicines to enhance performance, such as improving efficacy, safety
and compliance.

    Non-GAAP Financial Measures

    The company provides all information required in accordance with
GAAP, but it believes that evaluating its ongoing results of
operations may be difficult to understand if limited to reviewing only
GAAP financial results. In managing the company's business, management
reviews non-GAAP net loss and non-GAAP basic and diluted net loss per
common share which excludes, as applicable, SFAS 123R stock-based
compensation charges, litigation charges, and severance and
restructuring charges to evaluate the company's ongoing and future
financial and operating results.

    Management does not itself, nor does it suggest that investors
should, consider such non-GAAP financial measures in isolation from,
or as a substitute for, GAAP financial measures. The company considers
and presents such non-GAAP financial measures in measuring, reporting,
and forecasting its financial results to provide management and
investors with an additional tool to evaluate the company's operating
results in a manner that focuses on what management believes to be the
company's ongoing business operations. Management believes that the
inclusion of non-GAAP financial measures provides consistency and
comparability with past reports of financial results and future
projections of revenue and net loss financial measures. Investors
should note, however, that the non-GAAP financial measures used by the
company may not be the same non-GAAP financial measures as, and may
not be calculated in the same manner as that of other companies with
which investors may compare the financial results of the company.
Management believes it is useful for the company and investors to
review both GAAP information that includes the expenses and charges
mentioned above and the non-GAAP financial measures that exclude such
special expenses and charges to have a better understanding of the
overall performance of the company's business, its allocation of
resources and its ability to perform in the future. Investors are
encouraged to review the related GAAP financial measures and the
reconciliation of these non-GAAP financial measures to their most
directly comparable GAAP financial measure.

    This press release contains forward-looking statements that
reflect management's current views and expectations as to the Exubera
product commercial roll-out and market prospects, Exubera
manufacturing levels, clinical plans and expectations for the clinical
advancement of proprietary and partner products, prospects for the
business and financial objectives, and financial estimates for the
2006 and 2007 calendar years. These forward-looking statements involve
uncertainties and other risks, including but not limited to: (i) the
success of the Exubera commercial launch (ii) the company's and
Pfizer's ability to manufacture and supply sufficient quantities of
Exubera product to meet patient demand (iii) the discovery of any new
or more severe side effects or negative efficacy findings for Exubera
or any product liability claims related thereto (iv) investment in
proprietary products prior to seeking partner collaborations may
adversely impact results of operations and financial condition (v)
Nektar success or the success of Nektar's partners in obtaining
regulatory approvals (vi) a material negative impact on results of
operations for future periods as a result of the application of SFAS
123R related to expensing of stock-based compensation, and (vii)
additional charges and expenses that may be incurred as we restructure
the company in order to focus on our core assets. Other important
risks and uncertainties are detailed in the company's reports and
other filings with the SEC, including its most recent Annual Report on
Form 10-K, Quarterly Report on Form 10-Q, and Current Reports on Form
8-K. Actual results could differ materially from the forward-looking
statements contained in this press release. The company undertakes no
obligation to update forward-looking statements, whether as a result
of new information, future events or otherwise.

    Exubera is a registered trademark of Pfizer Inc.


                         NEKTAR THERAPEUTICS
           CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
            ( In thousands, except per share information)

                                   Unaudited           Unaudited
                              ------------------- --------------------
                              Three-Months Ended   Nine-Months Ended
                                 September 30,        September 30,
                              ------------------- --------------------
                                  2006      2005       2006      2005
                              --------- --------- ---------- ---------

Revenue:
        Contract research
         revenue               $15,111   $23,657    $44,250   $62,737
        Product sales and
         royalty revenue        41,451     8,450     98,005    20,313
        Exubera(R)
         commercialization
         readiness revenue       2,070     4,247      5,559    10,348
                              --------- -------------------- ---------
Total revenue                   58,632    36,354    147,814    93,398

Operating costs and expenses:
        Cost of goods sold      30,137     6,125     73,821    16,813
        Exubera(R)
         commercialization
         readiness costs         1,042     3,075      3,126     8,035
        Research and
         development            34,985    38,591    108,016   109,321
        General and
         administrative         14,442    10,948     60,878    30,193
        Litigation settlement        -         -     17,710         -
        Amortization of other
         intangible assets         708       982      3,331     2,945
                              --------- --------- ---------- ---------
Total operating costs and
 expenses                       81,314    59,721    266,882   167,307
                              --------- --------- ---------- ---------

Loss from operations           (22,682)  (23,367)  (119,068)  (73,909)

Loss on extinguishment of debt       -      (303)         -      (303)
Other income (expense), net      2,273       (32)     1,181    (1,435)
Interest income                  6,060     2,899     17,316     7,683
Interest expense                (5,255)   (2,992)   (15,335)   (8,908)
                              --------- --------- ---------- ---------

Loss before provision for
 income taxes                  (19,604)  (23,795)  (115,906)  (76,872)

Benefit (provision) for income
 taxes                               -         -          -         -
                              --------- --------- ---------- ---------

Net loss                      $(19,604) $(23,795) $(115,906) $(76,872)
                              ========= ========= ========== =========


Basic and diluted net loss per
 common share                   $(0.22)   $(0.28)    $(1.29)   $(0.90)

Shares used in computing basic
 and diluted net loss per
 share                          90,017    86,228     89,550    85,331


                         NEKTAR THERAPEUTICS
   Reconciliation of GAAP Financial Measures to Non-GAAP Financial
                               Measures
            ( In thousands, except per share information)


                                   Unaudited           Unaudited
                              ------------------- --------------------
                              Three-Months Ended   Nine-Months Ended
                                 September 30,        September 30,
                              ------------------- --------------------
                                2006      2005      2006       2005
                              --------- --------- ---------- ---------

GAAP net loss                 $(19,604) $(23,795) $(115,906) $(76,872)

Adjustments to GAAP net loss:

 SFAS 123R stock-based
  compensation expense,
  excluding severance            2,918         -     13,305         -
 Litigation settlement               -         -     17,710         -
 Severance and restructuring
  charges                        2,712         -     21,595         -
                              --------- --------- ---------- ---------

Non-GAAP net loss (1)         $(13,974) $(23,795)  $(63,296) $(76,872)
                              ========================================



GAAP basic and diluted net
 loss per common share          $(0.22)   $(0.28)    $(1.29)   $(0.90)

Adjustments to GAAP basic and diluted
 net loss per common share:

 SFAS 123R stock-based
  compensation expense,
  excluding severance            $0.03        $-      $0.15        $-
 Litigation settlement              $-        $-      $0.20        $-
 Severance and restructuring
  charges                        $0.03        $-      $0.24        $-
                              --------- --------- ---------- ---------

Non-GAAP basic and diluted net
 loss per common share (1)      $(0.16)   $(0.28)    $(0.71)   $(0.90)
                              ========= ========= ========== =========

Shares used in computing non-
 GAAP basic and diluted net
 loss per share                 90,017    86,228     89,550    85,331


(1) These non-GAAP financial measures are not presented as a measure
 of operating results and should not be construed as an alternative to
 either (i) income from operations or (ii) cash flows from operating
 activities. The company's management provides these non-GAAP
 financial measures to present investors with additional information
 that the company's management considers in assessing the company's
 results of operations, and to enhance investors' overall
 understanding of the company's financial performance.


                         NEKTAR THERAPEUTICS
                CONDENSED CONSOLIDATED BALANCE SHEETS
                            (In thousands)


                                            September 30, December 31,
                                                 2006         2005
                                             (unaudited)      (a)
                                            ------------- ------------

                   ASSETS

Current assets:
        Cash, cash equivalents and short-
         term investments                       $481,608     $476,201
        Inventory                                 15,795       18,627
        Other current assets                      49,029       25,015
                                            ------------- ------------
               Total current assets              546,432      519,843

Investments in marketable securities               9,342       90,222
Property and equipment, net                      136,580      142,127
Goodwill                                          78,431       78,431
Other intangible assets, net                       9,831       13,452
Other assets                                       9,404       14,479
                                            ------------- ------------
                                                $790,020     $858,554
                                            ============= ============


    LIABILITIES AND STOCKHOLDERS' EQUITY

Current liabilities:
        Accounts payable and accrued
         liabilities                             $40,633      $53,626
        Capital lease obligations - current          604          482
        Convertible subordinated notes and
         debentures - current                     36,026            -
        Deferred revenue - current                18,066       15,487
                                            ------------- ------------
               Total current liabilities          95,329       69,595

Convertible subordinated notes and
 debentures                                      381,627      417,653
Accrued rent                                       2,295        2,409
Capital lease obligations                         19,814       20,276
Deferred revenue                                  23,278        8,374
Other long-term liabilities                       15,994       13,436

Stockholders' equity:
        Preferred stock at par                         -            -
        Common stock at par                            9            9
        Capital in excess of par               1,269,341    1,233,690
        Deferred compensation                          -       (2,949)
        Accumulated other comprehensive
         loss                                        471       (1,707)
        Accumulated deficit                   (1,018,138)    (902,232)
                                            ------------- ------------
               Total stockholders' equity        251,683      326,811
                                            ------------- ------------
                                                $790,020     $858,554
                                            ============= ============


(a) The balance sheet at December 31, 2005 has been derived from the
 audited financial statements at that date but does not include all of
 the information and footnotes required by accounting principles
 generally accepted in the United States for complete financial
 statements.


                          Supplemental Table

                          NEKTAR THERAPEUTICS
   Reconciliation of Non-GAAP Projected Financial Guidance for 2006


Refer to the discussion of non-GAAP financial measures included in the
 accompanying press release for additional information.


                                                    2006 Projected
                                                   Financial Guidance
                                                 ---------------------

 2006 Exubera-related projected revenue range         $90  to    $100
 2006 other revenue                                   100         110
                                                 ---------     -------
2006 projected total revenue range                   $190  to    $210
                                                 =========     =======

Projected GAAP net loss                             $(155) to   $(170)

Adjustments to GAAP net loss:

 SFAS 123R stock-based compensation expense,
  excluding severance related charges                  22          22
 Litigation charges                                    18          18
 Severance and restructuring charges                   20          20
                                                 ---------     -------

Projected Non-GAAP net loss                          $(95) to   $(110)
                                                 =========     =======


                          Supplemental Table

                          NEKTAR THERAPEUTICS
   Reconciliation of Non-GAAP Projected Financial Guidance for 2007
                             (In millions)



Refer to the discussion of non-GAAP financial measures included in the
 accompanying press release for additional information.


                                                      2007 Projected
                                                         Financial
                                                          Guidance
                                                     -----------------

 2007 Exubera-related projected revenue range         $110  to   $130
 2007 other revenue                                    100        120
                                                     ------     ------
2007 projected total revenue range                    $210  to   $250
                                                     ======     ======

Projected GAAP net loss                              $(110) to  $(130)

Adjustments to GAAP net loss:

 SFAS 123R stock-based compensation expense,
  excluding severance related charges                   35         35

Projected Non-GAAP net loss                           $(75) to   $(95)
                                                     ======     ======

    CONTACT: Nektar Therapeutics
             Joyce Strand, 650-631-3138
             Jennifer Ruddock, 650-631-4954