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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 14A
Proxy Statement Pursuant to Section 14(a) of the Securities
Exchange Act of 1934 (Amendment No. )
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o   Soliciting Material Pursuant to §240.14a-12
(NEKTAR THERAPEUTICS)
Nektar Therapeutics
 
(Name of Registrant as Specified In Its Charter)
 
(Name of Person(s) Filing Proxy Statement, if other than the Registrant)
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(PROXY CARD)
*** Exercise Your Right to Vote *** Important Notice Regarding the Availability of Proxy Materials for the Stockholder Meeting to Be Held on June 14, 2011. Meeting Information NEKTAR THERAPEUTICS Meeting Type: Annual Meeting For holders as of: April 27, 2011 Date: June 14, 2011 Time: 2:00 PM Pacific Time Location: Nektar Therapeutics 455 Mission Bay Blvd. South San Francisco, CA 94158 You are receiving this communication because you hold NEKTAR THERAPEUTICS shares in the above named company. 455 MISSION BAY BOULEVARD SOUTH SAN FRANCISCO, CA 94158 This is not a ballot. You cannot use this notice to vote these shares. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. You may view the proxy materials online at www.proxyvote.com or easily request a paper copy (see reverse side). We encourage you to access and review all of the important information contained in the proxy materials before voting. See the reverse side of this notice to obtain M36564-P14067 proxy materials and voting instructions.

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(PROXY CARD)
Before You Vote How to Access the Proxy Materials Proxy Materials Available to VIEW or RECEIVE: NOTICE AND PROXY STATEMENT ANNUAL REPORT How to View Online: Have the information that is printed in the box marked by the arrow JXXXX XXXX XXXX (located on the following page) and visit: www.proxyvote.com. How to Request and Receive a PAPER or E-MAIL Copy: If you want to receive a paper or e-mail copy of these documents, you must request one. There is NO charge for requesting a copy. Please choose one of the following methods to make your request: 1) BY INTERNET: www.proxyvote.com 2) BY TELEPHONE: 1-800-579-1639 3) BY E-MAIL*: sendmaterial@proxyvote.com * If requesting materials by e-mail, please send a blank e-mail with the information that is printed in the box marked by the arrow JXXXX XXXX XXXX (located on the following page) in the subject line. Requests, instructions and other inquiries sent to this e-mail address will NOT be forwarded to your investment advisor. Please make the request as instructed above on or before May 31, 2011 to facilitate timely delivery. How To Vote Please Choose One of the Following Voting Methods Vote In Person: Many shareholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance. At the meeting, you will need to request a ballot to vote these shares. Vote By Internet: To vote now by Internet, go to www.proxyvote.com. Have the information that is printed in the box M36565-P14067 marked by the arrow JXXXX XXXX XXXX available and follow the instructions. Vote By Mail: You can vote by mail by requesting a paper copy of the materials, which will include a proxy card.

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(PROXY CARD)
Voting Items The Board of Directors recommends a vote “FOR” each nominee listed in Proposal 1 and “FOR” Proposals 2 and 3. 1. To elect three directors with terms to expire at the 2014 Annual Meeting of Stockholders; Nominees: 1a. Joseph J. Krivulka 1b. Howard W. Robin 1c. Dennis L. Winger 2. To ratify the selection of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2011. 3. Advisory vote on Executive Compensation. The Board of Directors recommends you vote for “1 Year” on the following proposal. 4. To recommend, by non-binding vote, the frequency of Executive Compensation votes. M36566-P14067

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(PROXY CARD)
M36567-P14067

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